H 77

SKU: orb1987082

Description

H 77 is a potent renin inhibitor derived from the angiotensinogen (6-13) octapeptide, featuring a reduced peptide bond (-CH2-NH-) replacing the standard Leu(10)-Leu(11) linkage. This analog is utilized in cardiovascular research to study the renin-angiotensin system in both in vitro biochemical assays and in vivo hypertension models.

Key Properties

• CAS Number: 82131-82-6
• MW: 1011.22
• Formula: C₅₂H₇₄N₁₂O₉
• SMILES: C(N[C@@H](CC1=CC=CC=C1)C(N[C@@H](CC2=CN=CN2)C(N[C@H](CN[C@H](C(N[C@H](C(N[C@@H](CC3=CC=C(O)C=C3)C(O)=O)=O)C(C)C)=O)CC(C)C)CC(C)C)=O)=O)(=O)[C@H]4N(C([C@@H](CC5=CN=CN5)N)=O)CCC4
• Target: Others

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

133836