Gypenoside LXXV

SKU: orb1691965

Description

Gypenoside LXXV is a ginseng-derived saponin that acts as a glucocorticoid receptor agonist, inducing nuclear translocation. This mechanism upregulates connective tissue growth factor (CTGF), supporting its investigation in wound healing models both in vitro and in vivo.

Research Area

Metabolism Research

Key Properties

• CAS Number: 110261-98-8
• MW: 785.03
• Purity: 98.66% (May vary between batches)
• Formula: C₄₂H₇₂O₁₃
• SMILES: [H][C@@]1(CC[C@]2(C)[C@]1([H])[C@H](O)C[C@]1([H])[C@@]3(C)CC[C@H](O)C(C)(C)[C@]3([H])CC[C@@]21C)[C@](C)(CCC=C(C)C)O[C@@H]1O[C@H](CO[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)[C@@H](O)[C@H](O)[C@H]1O
• Target: Glucocorticoid Receptor
• Solubility: DMSO:80.00 mg/mL (101.91 mM)

Bioactivity

• In Vitro:
  Gypenoside LXXV (1.0-100 μM, 48 hours) can dose-dependently inhibit the proliferation of three cancer cell lines (Homo sapiens cervical cancer cell line HeLa, mouse melanoma cell line B16, Homo sapiens breast cancer cell line MDA-MB-231). When the administration concentration reaches 50 μM, it can almost completely inhibit the proliferation of all tested cancer cells .

Storage & Handling

• Storage: keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Gypenoside LXXV

Compound Identifiers

PubChem CID

86289140