Gymnestrogenin

SKU: orb1684554

Description

Gymnestrogenin is a natural triterpenoid that functions as a liver X receptor (LXR) antagonist. This bioactive compound is utilized in biochemical research for studying lipid metabolism and inflammation, with applications in both in vitro and in vivo experimental models.

Research Area

Metabolism Research

Key Properties

• CAS Number: 19942-02-0
• MW: 490.72
• Formula: C₃₀H₅₀O₅
• SMILES: C(O)[C@]12[C@](C=3[C@@](C)(C[C@@H]1O)[C@@]4(C)[C@](CC3)([C@]5(C)[C@@](CC4)([C@@](CO)(C)[C@@H](O)CC5)[H])[H])(CC(C)(C)[C@@H](O)C2)[H]
• Target: Liver X Receptor
• Solubility: DMSO:≥ 40 mg/mL

Bioactivity

• Target IC50:
  LXRβ:1.4 μM|LXRα:2.5 μM
• In Vitro:
  In HepG2 cells, Gymnestrogenin exhibited dual antagonistic effects on liver X receptor α (LXRα) and β (LXRβ), with IC50 values of 2.5 μM and 1.4 μM, respectively .
  Read more...

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Gymnestrogenin, LiverXReceptor, Liver X Receptor

Compound Identifiers

PubChem CID

15560302