GW2974

SKU: orb3137058

Description

GW2974 is an orally active dual inhibitor of EGFR and ErbB2 (HER2) with IC50 values of 0.007 μM and 0.016 μM, respectively. It inhibits the invasion of glioblastoma multiforme (GBM) cells and tumor growth in vitro and in vivo.

Research Area

Cardiovascular Research, Signal Transduction

Key Properties

• CAS Number: 202272-68-2
• MW: 395.46
• Purity: 99.43% (May vary between batches)
• Formula: C₂₃H₂₁N₇
• SMILES: N=1C=NC(NC=2C=CC3=C(C=NN3CC=4C=CC=CC4)C2)=C5C=C(N=CC15)N(C)C
• Target: EGFR,HER

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

EGFR,HER