GW 627368X

SKU: orb1225049

Description

GW627368(GW627368X) is a novel, potent and selective competitive antagonist of prostanoid EP4 receptor(Ki= 100 nM) with additional human TP receptor affinity(Ki= 150 nM).

Key Properties

• CAS Number: 439288-66-1
• MW: 544.62
• Purity: >98% (HPLC)
• Formula: C₃₀H₂₈N₂O₆S
• SMILES: O=C(NS(=O)(C1=CC=CC=C1)=O)CC2=CC=C(N(CC3=C4C(OCC)=C(C=CC=C5)C5=C3OCC)C4=O)C=C2
• Target: Prostaglandin Receptor
• Solubility: DMSO: 10 mg/mL

Bioactivity

• In Vivo:
  Animal model: 6-8 weeks Swiss albino mice. Dosage: 0 mg/kg, 5 mg/kg, 10 mg/kg, 15 mg/kg, 15 mg/kg. Administration: Oral administration, every alternate day for 28 days. Result: Displayed anti-tumor and anti-proliferative potential in sarcoma 180 bearing mice.

Storage & Handling

• Storage: Storage temperature: -20°C. Stability: ≥ 2 years
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

GW627368X | GW 627368X | GW-627368X | GW627368

Quick Database Links

Gene Symbol

Prostaglandin Receptor