Gue1654

SKU: orb1700437

Description

Gue1654 is a selective OXE-R antagonist that protects against ischemic myocardial injury in mouse models and cardiomyocytes under oxygen/glucose deprivation. It exerts its cardioprotective effects by inhibiting PKC-ε/NF-κB signaling and apoptosis, making it a useful research tool for studying cardiovascular diseases.

Research Area

Immunology & Inflammation

Key Properties

• CAS Number: 397290-30-1
• MW: 447.6
• Purity: >98%
• Formula: C₂₃H₁₇N₃OS₃
• SMILES: CSC1=NC2=C(S1)C1=C(C=C2)N=C(NC(=O)C(C2=CC=CC=C2)C2=CC=CC=C2)S1
• Target: GPCR
• Solubility: Soluble in DMSO (up to 40 mg/ml with warming).

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

OXE-R, Gue 1654, Gue1654, Gue-1654, NFkB, NF-kB, NFκB

Compound Identifiers

PubChem CID

5066134