Guanosine 5'-monophosphate disodium salt

SKU: orb1221452

Description

Guanosine monophosphate also known as guanylic acid or 5'-GMP belongs to the class of organic compounds known as purine ribonucleoside monophosphates. In particular L-Glutamic acid and guanosine monophosphate can be biosynthesized from xanthylic acid and L-glutamine; which is catalyzed by the enzyme GMP synthase [glutamine-hydrolyzing]. In addition Guanosine triphosphate and guanosine monophosphate can be biosynthesized from diguanosine tetraphosphate; which is catalyzed by the enzyme bis(5'-nucleosyl)-tetraphosphatase [asymmetrical]. In humans guanosine monophosphate is involved in the kanamycin action pathway the telithromycin action pathway the tobramycin action pathway and the erythromycin action pathway. Guanosine monophosphate is also involved in several metabolic disorders some of which include the AICA-ribosiduria pathway adenosine deaminase deficiency adenine phosphoribosyltransferase deficiency (aprt) and the 2-hydroxyglutric aciduria (D and L form) pathway. Outside of the human body guanosine monophosphate can be found in a number of food items such as onion-family vegetables millet chinese water chestnut and red rice. This makes guanosine monophosphate a potential biomarker for the consumption of these food products.

Key Properties

• CAS Number: 5550-12-9
• MW: 425.2
• Purity: >98% (HPLC)
• Formula: C₁₀H₁₄N₅Na₂O₉P
• SMILES: O.[Na+].[Na+].Nc1nc2n(cnc2c(=O)[nH]1)[C@@H]1O[C@H](COP([O-])([O-])=O)[C@@H](O)[C@H]1O
• Target: Others
• Solubility: Water:200 mM

Storage & Handling

• Storage: Storage temperature: -20°C. Stability: ≥ 2 years
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

GMP-5

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