GTCpFE

SKU: orb2665474

Description

GTCpFE is a novel anti-inflammatory and anti-cancer stem cell agent derived from Dimethyl fumarate and Aspirin. It functions by inhibiting IKKα/β in the NF-κB pathway, blocking p65 nuclear translocation, and suppressing breast cancer stem cell markers like CD44+CD24- in mammosphere assays. This makes it a valuable research tool for studying NF-κB-driven inflammation and aggressive cancer phenotypes in vitro.

Research Area

Signal Transduction

Key Properties

• CAS Number: 1588866-45-8
• MW: 412.39
• Formula: C₂₂H₂₀O₈
• SMILES: C(OC1=CC=C(COC(/C=C/C(OCC)=O)=O)C=C1)(=O)C2=C(OC(C)=O)C=CC=C2
• Target: NF-κB

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

73425593