GTCpFE

• Catalog Number: orb2665474
• Category: Small Molecules
• Description: GTCpFE, a compound synthesized from Dimethyl fumarate (DMF) and Aspirin (ASA), inhibits IKKα/β in the NF-κB pathway, exhibiting anti-inflammatory activity by preventing p65 from entering the nucleus. It selectively inhibits cancer stem cell (CSC) activity by reducing the growth of mammospheres and the expression of the CD44+CD24- immune phenotype. Furthermore, GTCpFE targets breast cancer stem cells, crucial in aggressive cancer phenotypes that depend on NFκB and PGE2.
• CAS Number: 1588866-45-8
• Purity: 98.00%
• MW: 412.39
• SMILES: C(OC1=CC=C(COC(/C=C/C(OCC)=O)=O)C=C1)(=O)C2=C(OC(C)=O)C=CC=C2
• Formula: C₂₂H₂₀O₈
• Storage: -20°C
• Note: For research use only
• Expiration Date: 12 months from date of receipt.