GSTO1-IN-3

SKU: orb3173837

Description

GSTO1-IN-3 is a potent inhibitor of GSTO1-1, with an IC50 value of 0.11 μM, and exhibits selectivity towards GSTO2-2, GSTA1-1, and GSTP1-1 (IC50> 100 μM). It enhances the cytotoxic effects of Cisplatin on human breast cancer cells and inhibits IL-1β release in mouse bone marrow-derived macrophages (BMDM). Additionally, GSTO1-IN-3 reduces inflammation in mice and is applicable for research related to breast cancer and inflammation.

Research Area

Immunology & Inflammation, Metabolism Research

Key Properties

• CAS Number: 158890-32-5
• MW: 251.752
• Formula: C₁₄H₁₈ClNO
• SMILES: ClCC(=O)N1CCC(CC2=CC=CC=C2)CC1
• Target: GST,Interleukin

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

GST,Interleukin