GSPT1 degrader-4

SKU: orb2564610

Description

GSPT1 degrader-4 (3) is a molecular glue that induces GSPT1 degradation with a DC₅₀ of 25.4 nM. It inhibits CAL51 breast cancer cell proliferation with an IC₅₀ of 39 nM, making it a useful chemical probe for targeted protein degradation research in oncology, both in vitro and in vivo.

Research Area

Pharmacology & Drug Discovery

Key Properties

• CAS Number: 3034764-32-1
• MW: 480.90
• Formula: C₂₄H₂₁ClN₄O₅
• SMILES: O=C(OCC=1C=CC2=C(C1)C=C3N2C(=O)N(C3)C4C(=O)NC(=O)CC4)NC5=CC=C(C(Cl)=C5)C
• Target: Molecular Glues

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

171488069