GSK9027

SKU: orb1704501

Description

GSK9027 is a nonsteroidal, partial agonist of the glucocorticoid receptor (GR). It exhibits lower transcriptional activity than dexamethasone in 2×GRE reporter assays. This compound is a valuable research tool for investigating partial GR activation in both cellular and animal models of inflammation and immune regulation.

Research Area

Metabolism Research

Key Properties

• CAS Number: 1229096-88-1
• MW: 525.52
• Purity: 99.36% (May vary between batches)
• Formula: C₂₇H₁₉F₄N₃O₂S
• SMILES: FC1=CC=C(N2C=3C(=CC(=CC3)C4=C(C(F)(F)F)C=C(NS(CC5=CC=CC=C5)(=O)=O)C=C4)C=N2)C=C1
• Target: Glucocorticoid Receptor
• Solubility: DMSO:60 mg/mL (114.17 mM)

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

GSK-9027, GSK9027, GSK 9027, GR agonist 23a, GlucocorticoidReceptor, Glucocorticoid Receptor

Compound Identifiers

PubChem CID

24882669