GSK8573

SKU: orb1707238

Description

GSK8573 is an inactive structural analog of the BRD9 inhibitor GSK2801, serving as a negative control compound. It binds to BRD9 with a Kd of 1.04 µM and is used in both in vitro and in vivo studies to validate the on-target effects of bromodomain inhibitors in epigenetics and cancer research.

Research Area

Epigenetics & Chromatin

Key Properties

• CAS Number: 1693766-04-9
• MW: 323.39
• Purity: 99.97% (May vary between batches)
• Formula: C₂₀H₂₁NO₃
• SMILES: CCCOc1ccn2c(cc(-c3cccc(OC)c3)c2c1)C(C)=O
• Target: Epigenetic Reader Domain
• Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (6.18 mM);DMSO:22 mg/mL (68.03 mM)

Bioactivity

• Target IC50:
  BRD9:1.04 μM (Kd)

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

control compound, BRD9, biological, BAZ2A, BAZ2B, EpigeneticReaderDomain, Epigenetic Reader Domain, GSK 8573, GSK8573, GSK-8573, Inhibitor, inhibit

Compound Identifiers

PubChem CID

121230107