GSK4418959 (enantiomer)

SKU: orb3145060

Description

GSK4418959 enantiomer is the enantiomer of GSK4418959. GSK4418959 (IDE275) is a non-covalent, reversible, selective helicase inhibitor of WRN with oral bioavailability. It competitively inhibits ATPase and DNA unwinding functions in an ATP-dependent manner. GSK4418959 is utilized in the study of microsatellite instability-high (MSI-H) cancer.

Research Area

Cell Biology, Molecular Biology

Key Properties

• CAS Number: 3064599-37-4
• MW: 646.65
• Formula: C₃₁H₃₀F₄N₄O₅S
• SMILES: C(O)(=O)[C@H]1[C@@H](CCC[C@@H]1C(NC2=C(F)C=C(C(F)(F)F)C=C2)=O)C3=CC=C(N(S(=O)(=O)C=4C=C5C(=CC4)N(C)C(C)=N5)C)C=C3
• Target: DNA/RNA Synthesis

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

DNA/RNA Synthesis