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GSK343

SKU: orb1226482

Description

GSK343 is a potent and selective EZH2 inhibitor with IC50 of 4 nM, showing 60 fold selectivity against EZH1, and >1000 fold selectivity against other histone methyltransferases.

Images & Validation

Key Properties

CAS Number1346704-33-3
MW541.69
Purity>98% (HPLC)
FormulaC31H39N7O2
SMILESO=C(C1=CC(C2=CC(N3CCN(C)CC3)=NC=C2)=CC4=C1C=NN4C(C)C)NCC5=C(CCC)C=C(C)NC5=O
TargetHMTase
SolubilityEthanol: 4 mg/mL (7.38 mM); DMSO: 1 mg/mL warmed (1.84 mM)

Storage & Handling

StorageStorage temperature: -20°C. Stability: ≥ 2 years
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

GSK343 | GSK-343 | GSK 343

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Protocol Information

GSK343 (orb1226482)

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Available Sizes

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200 mg
500 mg
5 mg
$ 100.00
10 mg
$ 130.00
25 mg
$ 240.00
50 mg
$ 380.00
100 mg
$ 660.00