GSK3368715 hydrochloride

SKU: orb2283276

Description

GSK3368715 is a potent, orally bioavailable, and SAM-noncompetitive Type I PRMT inhibitor with low nM IC50 values. It demonstrates broad anti-tumor activity in preclinical models, alters RNA splicing, and shows synergistic tumor growth inhibition when combined with the Type II PRMT inhibitor GSK3326595. This molecule is a valuable tool for investigating PRMT biology in cancer research, both in vitro and in vivo.

Research Area

Epigenetics & Chromatin

Key Properties

• CAS Number: 2227587-25-7
• MW: 403
• Formula: C₂₀H₃₈N₄O₂.HCl
• SMILES: C(OCC)C1(COCC)CCC(CC1)C=2C(CN(CCNC)C)=CNN2.Cl
• Target: Histone Methyltransferase,Others

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

90462879