GSK3-IN-4

SKU: orb1685682

Description

GSK3-IN-4 is a potent small molecule inhibitor of both GSK-3α and GSK-3β isoforms, exhibiting IC50 values ranging from 0.101 to 1 μM in biochemical assays. This compound is a valuable research tool for investigating glycogen synthase kinase 3 signaling pathways in cellular models of neurological disorders, diabetes, and cancer.

Research Area

Signal Transduction, Stem Cell & Developmental Biology

Key Properties

• CAS Number: 748145-19-9
• MW: 308.38
• Purity: 98.33% (May vary between batches)
• Formula: C₁₈H₂₀N₄O
• SMILES: O=C1C=2C(C3=C(NC2CC(C)(C)C1)NN=C3C)C=4C=CC=NC4
• Target: GSK-3
• Solubility: DMSO:50 mg/mL (162.14 mM)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

GSK3, GSK3-IN-4, GSK-3α/β, WAY606956

Compound Identifiers

PubChem CID

3809721