GSK3-IN-10

SKU: orb3028647

Description

GSK3-IN-10 (Compound 4) is a multi-target inhibitor primarily affecting GSK3α and GSK3β with IC50 values of 1.0 nM and 2.0 nM, respectively. It inhibits the activation of β-catenin, enhances neuronal survival, and provides protective effects against endoplasmic reticulum stress.

Research Area

Cell Biology, Signal Transduction, Stem Cell & Developmental Biology

Key Properties

• CAS Number: 844441-56-1
• MW: 364.347
• Formula: C₁₇H₁₈F₂N₄O₃
• SMILES: O=C(NCC1CCOCC1)C2=NNC=C2NC(=O)C=3C(F)=CC=CC3F
• Target: Wnt/beta-catenin,Others,DYRK,GSK-3,CDK,JNK

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

Wnt/beta-catenin,Others,DYRK,GSK-3,CDK,JNK