GSK2983559 free acid

SKU: orb1309600

Description

GSK2983559 free acid is a potent and selective RIP2 kinase inhibitor. It effectively blocks proinflammatory cytokine production, as demonstrated in human inflammatory bowel disease explant models, supporting its utility for in vitro and in vivo research on NOD2 signaling and inflammatory pathologies.

Research Area

Cell Biology, Signal Transduction

Key Properties

• CAS Number: 1579965-12-0
• MW: 538.53
• Purity: 99.56% (May vary between batches)
• Formula: C₂₁H₂₃N₄O₇PS₂
• SMILES: N(C=1C2=C(C=C(OCCOP(=O)(O)O)C(S(C(C)(C)C)(=O)=O)=C2)N=CN1)C=3C=C4C(=CC3)SC=N4
• Target: RIP kinase
• Solubility: DMSO:4.5 mg/mL (8.36 mM)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Receptor-interacting protein kinases, THP-1 cell, RIPK, RIPkinase, RIP kinase, RIP2, GSK 2983559, GSK2983559, GSK-2983559, GSK2983559 free acid, GSK-2983559 free acid, inhibit, Inhibitor

Compound Identifiers

PubChem CID

73386708