GSK2850163 hydrochloride

SKU: orb1686842

Description

GSK2850163 hydrochloride is a potent and selective dual inhibitor of IRE1α, targeting both its kinase and RNase activities with IC50 values of 20 nM and 200 nM, respectively. This small molecule is a valuable research tool for investigating the unfolded protein response in models of cancer and neurodegenerative diseases, both in vitro and in vivo.

Research Area

Cell Biology

Key Properties

• CAS Number: 2319838-09-8
• MW: 482.87
• Formula: C₂₄H₃₀Cl₃N₃O
• SMILES: C(N1C[C@]2(CN(C(NCC3=CC=C(C)C=C3)=O)CCC2)CC1)C4=CC(Cl)=C(Cl)C=C4.Cl
• Target: IRE1,Others

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

132472232