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GSK235

SKU: orb3174314

Description

GSK235 is an orally active and selective allosteric inhibitor of endoplasmic reticulum aminopeptidase 1 (ERAP1), boasting pIC50 values of 8.45 and 7.59 for human and murine ERAP1, respectively. It demonstrates over 1000-fold selectivity against the highly homologous enzymes ERAP2 and IRAP. GSK235 modulates the immunopeptidome of cancer cells, enhancing their antigenicity, and is applicable in colorectal cancer and arthritis research.

Research Area

Metabolism Research

Images & Validation

Key Properties

TargetAminopeptidase

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
Quality Guarantee

Quality Guarantee

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Protocol Information