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GSK2018682

SKU: orb1299885

Description

GSK2018682 is a potent and selective agonist for the S1P₁ and S1P₅ receptors, with pEC₅₀ values of 7.7 and 7.2, respectively. This small molecule is a valuable research tool for investigating sphingosine-1-phosphate signaling in immunological and neurological studies, applicable in both cellular and animal models of inflammation and autoimmunity.

Research Area

Pharmacology & Drug Discovery

Images & Validation

Key Properties

CAS Number1034688-30-6
MW440.88
Purity97.78% (May vary between batches)
FormulaC22H21ClN4O4
SMILESCC(C)Oc1ncc(cc1Cl)-c1nc(no1)-c1cccc2n(CCCC(O)=O)ccc12
TargetLPL Receptor,S1P Receptor
SolubilityDMSO:125 mg/mL (283.52 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (9.07 mM)

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

S1P, S1P Receptor, S1PReceptor, inhibit, Inhibitor, LPL, LPL Receptor, LPLReceptor, Lysophospholipid Receptor, GSK 2018682, GSK2018682, GSK-2018682

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Quality Guarantee

Quality Guarantee

Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our Terms & Conditions and Buying Guide. Contact us at [email protected].

Key Properties

No computed properties available.

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Protocol Information

GSK2018682 (orb1299885)

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% DMSO +
%+
% Tween 80 +
%

Available Sizes

Select a size below

2 mg
$ 70.00
5 mg
$ 90.00
1 ml x 10 mM (in DMSO)
$ 100.00
10 mg
$ 120.00
25 mg
$ 200.00
50 mg
$ 330.00
100 mg
$ 470.00
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