GSK2018682

SKU: orb1299885

Description

GSK2018682 is a potent and selective agonist for the S1P₁ and S1P₅ receptors, with pEC₅₀ values of 7.7 and 7.2, respectively. This small molecule is a valuable research tool for investigating sphingosine-1-phosphate signaling in immunological and neurological studies, applicable in both cellular and animal models of inflammation and autoimmunity.

Research Area

Pharmacology & Drug Discovery

Key Properties

• CAS Number: 1034688-30-6
• MW: 440.88
• Purity: 99.04% (May vary between batches)
• Formula: C₂₂H₂₁ClN₄O₄
• SMILES: CC(C)Oc1ncc(cc1Cl)-c1nc(no1)-c1cccc2n(CCCC(O)=O)ccc12
• Target: S1P Receptor,LPL Receptor
• Solubility: DMSO:125 mg/mL (283.52 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (9.07 mM)

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

S1P, S1P Receptor, S1PReceptor, inhibit, Inhibitor, LPL, LPL Receptor, LPLReceptor, Lysophospholipid Receptor, GSK 2018682, GSK2018682, GSK-2018682

Compound Identifiers

PubChem CID

24988201