GSK1940029

SKU: orb1301798

Description

GSK1940029 is a potent and selective small molecule inhibitor of stearoyl-CoA desaturase (SCD). It is a valuable research tool for investigating SCD's role in metabolic diseases, such as obesity and fatty liver, in both cellular and animal models.

Research Area

Metabolism Research

Key Properties

• CAS Number: 1150701-66-8
• MW: 391.25
• Purity: 99.49%
• Formula: C₁₈H₁₆Cl₂N₄O₂
• SMILES: Cc1c(nnn1Cc1ccc(Cl)c(Cl)c1)C(=O)Nc1ccc(CO)cc1
• Target: Stearoyl-CoA Desaturase (SCD),Dehydrogenase
• Solubility: DMSO:30 mg/mL (76.68 mM)

Bioactivity

• In Vitro:
  GSK1940029 is a stearoyl-coa desaturase (SCD) , methods of synthesis and uses in treating and/or preventing various diseases, including those mediated by SCD enzyme, such as diseases related to elevated lipid levels, cardiovascular disease, diabetes, obesity, metabolic syndrome, skin disorders such as acne, diseases or conditions related to cancer.

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Alzheimer's, cancer, cardiovascular,diabetes, obesity, metabolic, inhibit, GSK1940029, GSK-1940029, GSK 1940029, elevated, enzyme, Inhibitor, Stearoyl-CoA Desaturase (SCD), StearoylCoADesaturase(SCD), Stearoyl-CoA Desaturase, StearoylCoADesaturase, StearoylCoA Desaturase (SCD), syndrome, SCD, SCD inhibitor 1, SCD inhibitor1, SCD inhibitor-1

Compound Identifiers

PubChem CID

42603008