GSK-J1 lithium salt

SKU: orb1909579

Description

GSK-J1 lithium salt is a potent and selective small molecule inhibitor of the H3K27me3/me2 demethylases JMJD3 (KDM6B) and UTX (KDM6A), exhibiting an IC50 of 60 nM against KDM6B. This inhibitor is widely used in vitro and in vivo to investigate the role of these epigenetic regulators in cancer, immunology, and stem cell biology.

Research Area

Epigenetics & Chromatin

Images & Validation

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Key Properties

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CAS Number	2309668-29-7
MW	395.38
Formula	C₂₂H₂₂LiN₅O₂
SMILES	[Li]OC(CCNC1=NC(C2=NC=CC=C2)=NC(N(CC3)CCC4=C3C=CC=C4)=C1)=O
Target	Histone Demethylase

Storage & Handling

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Storage	-20°C
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

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Compound Identifiers

PubChem CID

78357797 ↗

Key Properties

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No computed properties available.

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