GSK 591 dihydrochloride

SKU: orb1693271

Description

This compound is a potent and selective PRMT5 inhibitor with an IC50 of 4 nM, demonstrating anti-proliferative activity in mantle cell lymphoma models. It is a valuable chemical probe for investigating PRMT5 biology in cancer research, including studies of splicing regulation and cellular differentiation.

Research Area

Epigenetics & Chromatin

Key Properties

• CAS Number: 2320953-89-5
• MW: 453.41
• Formula: C₂₂H₃₀Cl₂N₄O₂
• SMILES: Cl.Cl.O[C@@H](CNC(=O)c1ccnc(NC2CCC2)c1)CN1CCc2ccccc2C1
• Target: Others,Histone Methyltransferase

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

124201849