GSK-364735

SKU: orb1740963

Description

GSK-364735 is a small molecule inhibitor targeting HIV-1 integrase, exhibiting potent antiviral activity. It is a valuable research tool for studying retroviral infection mechanisms and has been utilized in both in vitro enzymatic assays and cellular models of HIV-1 replication.

Research Area

Infectious Disease & Virology, Protein Biochemistry

Key Properties

• CAS Number: 863434-13-3
• MW: 371.36
• Purity: 97.73% (May vary between batches)
• Formula: C₁₉H₁₈FN₃O₄
• SMILES: O=C(NCCO)C=1C(=O)N(C=2C=C(C=NC2C1O)CC3=CC=C(F)C=C3)C
• Target: HIV Protease

Bioactivity

• Target IC50:
  HIV-1:8 nM
• In Vitro:
  GSK-364735 is a potent anti-human immunodeficiency virus type 1 (HIV-1) drug that inhibits viral integrase with an inhibitory half concentration (IC50) of 8 nM.
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Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

S/GSK364735, S/GSK-364735, S364735, S-364735, GSK364735, GSK-364735, GSK 364735, HIV Protease, HIV Integrase, HIV-1, HIVProtease

Compound Identifiers

PubChem CID

54718859