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GSK-3β inhibitor 11

SKU: orb1688228

Description

Compound 21 is a potent GSK-3β inhibitor with an IC50 of 10.02 µM. It is a valuable research tool for investigating neurodegenerative disease pathways, including tau phosphorylation, in both cellular and animal models of Alzheimer's disease.

Research Area

Pharmacology & Drug Discovery

Images & Validation

Key Properties

CAS Number536731-65-4
MW393.42
Purity97.40% (May vary between batches)
FormulaC20H15N3O4S
SMILESCOc1cccc(c1)-c1csc(NC(=O)CN2C(=O)c3ccccc3C2=O)n1
TargetGSK-3
SolubilityDMSO:3.94 mg/mL (10.01 mM)

Bioactivity

Target IC50
GSK-3β:10.02 μM

Storage & Handling

StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

GSK-3, GSK3

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Key Properties

No computed properties available.

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GSK-3β inhibitor 11 (orb1688228)

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Available Sizes

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5 mg
$ 70.00
1 ml x 10 mM (in DMSO)
$ 90.00
10 mg
$ 90.00
25 mg
$ 140.00
50 mg
$ 200.00
100 mg
$ 290.00
200 mg
$ 390.00
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