GSK-3β-IN-28

SKU: orb3173219

Description

GSK-3β inhibitor 28 is a selective, non-competitive inhibitor of glycogen synthase kinase-3β (GSK-3β), with an IC50 value of 14.82 nM. It enhances the expression of phosphorylated GSK-3β while reducing the levels of p-NF-κB, P65, C-myc, and Cyclin D1. This compound induces apoptosis, causes G1 phase arrest, and inhibits cell migration. GSK-3β inhibitor 28 is applicable for cancer research, including studies on colorectal cancer.

Research Area

Cell Biology, Signal Transduction, Stem Cell & Developmental Biology

Key Properties

• Target: NF-κB,Apoptosis,GSK-3,c-Myc

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

NF-κB,Apoptosis,GSK-3,c-Myc