GSI-18

SKU: orb2665345

Description

GSI-18 is a γ-secretase inhibitor that blocks Notch signaling, thereby suppressing anchorage-independent growth in pancreatic cancer cells. This small molecule is a valuable research tool for investigating Notch pathway roles in pancreatic cancer, with applications in both in vitro and in vivo oncology studies.

Research Area

Neuroscience, Protein Biochemistry, Stem Cell & Developmental Biology

Key Properties

• CAS Number: 362653-62-1
• MW: 333.47
• Formula: C₁₇H₁₉NO₂S₂
• SMILES: N(S(=O)(=O)C1=CC=CS1)[C@H]2[C@]3(CC=4C(C[C@@]2(CC3)[H])=CC=CC4)[H]
• Target: Gamma-secretase

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

70640458