GS143

SKU: orb1305334

Description

GS143

Research Area

Protein Biochemistry, Signal Transduction

Key Properties

• CAS Number: 916232-21-8
• MW: 466.46
• Purity: 97.67% (May vary between batches)
• Formula: C₂₈H₁₉FN₂O₄
• SMILES: OC(=O)c1ccc(cc1)N1N=C(Cc2ccccc2)\C(=C/c2ccc(o2)-c2ccccc2F)C1=O
• Target: E1/E2/E3 Enzyme,IκB/IKK,NF-κB
• Solubility: 10% DMSO+90% Corn Oil:2 mg/mL (4.29 mM);DMSO:40 mg/mL (85.75 mM)

Bioactivity

• Target IC50:
  IκBα phosphorylation:5.2 μM

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Ubiquitin activating enzyme, Ubiquitin conjugating enzyme, Ubiquitin ligase, βTrCP1, ubiquitination, Th2, GS 143, GS143, GS-143, eosinophil, E3Enzyme, E3 ligating enzyme, IkB, IkB/IKK, Inhibitor, I kappa B kinase, IκB kinase, IκB, IκBα phosphorylation, IκBα, inhibit, inflammation, IKK, IL-4, Nuclear factor-kappaB, Nuclear factor-κB, NF-κB, NF-kB, NFkB, NFκB, anti-asthma, airway, E3 Enzyme, E2Enzyme, E1Enzyme, E2 conjugating enzyme, E2 Enzyme, E1 activating enzyme, E1 Enzyme, E1/E2/E3 Enzyme

Compound Identifiers

PubChem CID

121513876