GRPR antagonist-1

SKU: orb1686093

Description

GRPR antagonist-1 is a potent small molecule antagonist of the gastrin-releasing peptide receptor, demonstrating cytotoxic activity against various cancer cell lines including PC3, Pan02, and HGC-27 cells. Its pro-apoptotic mechanism involves modulating Bcl-2 family proteins, reducing Bcl-2 and increasing Bax levels, making it a valuable tool for oncology research in both in vitro and in vivo studies.

Research Area

Pharmacology & Drug Discovery

Key Properties

• MW: 558.59
• Formula: C₂₉H₃₃F₃N₄O₄
• Target: Others,Bombesin Receptor

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

Others,Bombesin Receptor