GRK6-IN-1

SKU: orb1687526

Description

GRK6-IN-1 is a potent and selective GRK6 inhibitor (IC50 = 120 nM). It serves as a valuable chemical probe for investigating GRK6's role in oncology, particularly in preclinical studies of multiple myeloma and triple-negative breast cancer using cellular and animal models.

Research Area

Cell Biology, Epigenetics & Chromatin, Pharmacology & Drug Discovery, Signal Transduction

Key Properties

• CAS Number: 2677786-61-5
• MW: 438.91
• Purity: 99.37% (May vary between batches)
• Formula: C₂₂H₂₃ClN₆O₂
• SMILES: CCc1cc(Nc2nc(NCc3ccc(Cl)cc3OC)nc3cccc(OC)c23)n[nH]1
• Target: Aurora Kinase,IGF-1R,GRK
• Solubility: DMSO:30 mg/mL (68.35 mM)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

GRK6

Compound Identifiers

PubChem CID

163196291