GRK5-IN-3

SKU: orb1687444

Description

GRK5-IN-3 is a potent, covalent small-molecule inhibitor targeting GRK5 and GRK6, with IC50 values of 0.22 µM and 0.41 µM, respectively. This compound is a valuable research tool for investigating GRK5/6 roles in cardiac function, cancer progression, and inflammation through in vitro biochemical and cellular assays.

Research Area

Cell Biology, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 2410793-22-3
• MW: 443.46
• Formula: C₂₃H₂₁N₇O₃
• SMILES: N(C1=C2C(=NC(NC3=C(OC)C=C(NC(C=C)=O)C=C3)=N1)NC=C2)C4=C(C(N)=O)C=CC=C4
• Target: GRK,Others

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

155530668