Graveoline

SKU: orb1297035

Description

Graveoline is a small molecule research compound that functions as an inducer of both apoptosis and autophagy. It has been investigated in in vitro studies for its effects on skin melanoma cell lines, highlighting its potential utility in cancer research and cell death mechanism studies.

Research Area

Cardiovascular Research, Cell Biology, Epigenetics & Chromatin, Immunology & Inflammation, Infectious Disease & Virology, Signal Transduction, Stem Cell & Developmental Biology

Key Properties

• CAS Number: 485-61-0
• MW: 279.29
• Purity: 98.14% (May vary between batches)
• Formula: C₁₇H₁₃NO₃
• SMILES: Cn1c(cc(=O)c2ccccc12)-c1ccc2OCOc2c1
• Target: Autophagy
• Solubility: DMSO:5.2 mg/mL (18.62 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (3.58 mM)

Bioactivity

• In Vitro:
  Results of MTT assay revealed that, in case of A375 cells,the cell viability gradually decreased upon administration of minimal concentration to the higher ones of graveoline. Upon treatment with 22.23 ± 0.79 μg/mL of graveoline,the cell viability reduced to 50% .
  Read more...

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

autophagy, 2-(Benzo[d][1,3]dioxol-5-yl)-1-methylquinolin-4(1H)-one, Foliosine, Graveoline

Compound Identifiers

PubChem CID

353825