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GPX4-IN-22

SKU: orb3210570

Description

GPX4-IN-22 is a GPX4 inhibitor and a ferroptosis (ferroptosis) inducer. It inhibits GPX4 enzyme activity and enhances ubiquitination-dependent proteasomal degradation of the GPX4 protein. GPX4-IN-22 induces ferroptosis by increasing lipid ROS and MDA levels in cancer cells while reducing glutathione levels. Additionally, GPX4-IN-22 suppresses cancer cell proliferation and colony formation, making it useful in colorectal cancer research.

Images & Validation

Key Properties

TargetFerroptosis,Glutathione Peroxidase,ROS

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Protocol Information