GPX4-IN-16

SKU: orb2945200

Description

GPX4-IN-16 ((R)-9i) is a potent and selective GPX4 inhibitor with a KD of 20.4 nM. It induces ferroptotic cell death and demonstrates cytotoxic and anticancer activity in cellular assays, making it a valuable research tool for studying ferroptosis in oncology.

Research Area

Metabolism Research

Key Properties

• MW: 540.656
• Formula: C₂₉H₂₄N₄O₃S₂
• SMILES: CC(C)(C)NC(=O)[C@@H](C1=CSC2=CC=CC=C21)N(C3=CC=C(C=C3)C4=CN=CO4)C(=O)C5=CSC(=N5)C#C
• Target: Glutathione Peroxidase

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

172676882