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GPX4-IN-15

SKU: orb2802238

Description

GPX4-IN-15 (C1) is a GPX4 inhibitor with 19.8% inhibition at 1 µM. It potently suppresses the proliferation of triple-negative breast cancer cell lines MDA-MB-468, BT-549, and MDA-MB-231, with IC50 values ranging from 0.48 to 0.96 µM, making it a useful tool for studying ferroptosis in cancer research.

Research Area

Metabolism Research, Neuroscience

Images & Validation

Key Properties

CAS Number3032966-42-7
MW368.21
FormulaC17H15Cl2NO4
SMILESO=C(OC)C1=CC=C(C=C1)N(C(=O)CCl)C2=CC=C(OC)C(Cl)=C2
TargetGlutathione Peroxidase,Cholinesterase (ChE)

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Key Properties

No computed properties available.

Protocol Information