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GPX4 24

SKU: orb1980026

Description

GPX4 24 is a potent, covalent GPX4 inhibitor derived from (1S,3R)-RSL3. It induces ferroptosis in vitro (EC50 = 0.16 µM in HT-1080 cells) and elevates lipid peroxidation markers like MDA in vivo, making it a valuable tool for studying ferroptosis in cancer research.

Images & Validation

Key Properties

MW460.93
FormulaC22H21ClN2O5S
SMILESClCC(N1[C@H](CC(C2=CC=CC=C2N3)=C3[C@@H]1C4=CC=C(C=C4)S(C)(=O)=O)C(OC)=O)=O
TargetOthers

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Key Properties

No computed properties available.

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Protocol Information

GPX4 24 (orb1980026)

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Step 1: Enter information below

(Recommended: An additional animal making an allowance for loss during the experiment)

Step 2: Enter the in vivo formulation

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