GPS167

SKU: orb3136980

Description

GPS167 is a specific small-molecule splicing regulator and SRSF10 inhibitor that modulates BCLAF1 alternative splicing with an IC50 of 2 μM in human colorectal HCT116 cells, while also directly inhibiting CLK1, CLK2, and CLK4 but not SRPK1 or DYRK1A, positioning it as a mechanistically well-defined probe for studying spliceosome regulation and kinase-dependent RNA processing.

Key Properties

• CAS Number: 3034312-19-8
• MW: 335.38
• Purity: 99.13% (May vary between batches)
• Formula: C₁₇H₁₃N₅OS
• SMILES: O=C(NC=1C=CC=2NN=CC2C1)C=3N=C(SC3)NC=4C=CC=CC4
• Target: Others

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

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