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GPR34 receptor antagonist 3

SKU: orb1942502

Description

Compound 5e is a potent and selective GPR34 antagonist that inhibits lysophosphatidylserine-induced ERK1/2 phosphorylation with an IC50 of 0.680 µM, exhibiting no significant cytotoxicity. This tool compound demonstrates in vivo efficacy by reducing neuropathic pain in a mouse model, supporting research into neuroinflammation and immune cell signaling pathways.

Research Area

Pharmacology & Drug Discovery, Signal Transduction

Images & Validation

Key Properties

TargetOthers

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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