GPR110 peptide agonist P12

• Catalog Number: orb2645945
• Category: Small Molecules
• Description: GPR110 peptide agonist P12 is a peptide that acts as an agonist for GPR110. This compound markedly enhances the initial rate of G protein GTPγS binding stimulated by GPR110. It mimics the action of the natural ligand, causing the extracellular domain (ECD) of GPR110 to dissociate from the seven-transmembrane domain (7TM) and exposing the N-terminal β-strand-13/stalk region of the 7TM domain, which acts as the agonist activating G protein signaling. GPR110 peptide agonist P12 is applicable in research related to developmental disorders and cancers associated with GPR110.
• CAS Number: 1778685-49-6
• Purity: 98.00%
• MW: 1325.57
• SMILES: C(N[C@@H](CC1=CC=CC=C1)C(N[C@H](C(=O)N2[C@H](C(O)=O)CCC2)[C@@H](C)C)=O)(=O)[C@H]3N(C([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](CC4=CC=CC=C4)NC([C@@H](NC([C@H]([C@@H](C)O)N)=O)CO)=O)=O)CO)=O)[C@H](CC)C)=O)CC(C)C)=O)CCSC)=O)CO)=O)CCC3
• Formula: C₆₃H₉₆N₁₂O₁₇S
• Storage: -20°C
• Note: For research use only
• Expiration Date: 12 months from date of receipt.