GPP78

SKU: orb1707252

Description

GPP78 is a potent and selective Nampt inhibitor with an IC50 of 3.0 nM for NAD depletion. It demonstrates cytotoxicity in neuroblastoma SH-SY5Y cells via autophagy induction (IC50: 3.8 nM), supporting its investigation in cancer and inflammation research both in vitro and in vivo.

Research Area

Cell Biology, Metabolism Research

Key Properties

• CAS Number: 1202580-59-3
• MW: 439.55
• Formula: C₂₇H₂₉N₅O
• SMILES: N(C(CCCCCCCN1C=C(N=N1)C=2C=CC=NC2)=O)C3=C(C=CC=C3)C4=CC=CC=C4
• Target: NAMPT,Autophagy

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

44819697