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GPI-15427

SKU: orb1740817

Description

GPI-15427 is a brain-penetrant, nanomolar-potency PARP-1 inhibitor. It enhances the efficacy of temozolomide and radiotherapy in CNS tumors and HNSCC, as demonstrated in preclinical in vitro and in vivo studies for glioblastoma and lymphoma research.

Research Area

Epigenetics & Chromatin, Metabolism Research, Molecular Biology

Images & Validation

Key Properties

CAS Number805242-85-7
MW348.4
FormulaC20H20N4O2
SMILESO=C1C2=C3C(C=4C(OC3=CC=C2)=CC=C(CN5CCN(C)CC5)C4)=NN1
TargetOthers

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Key Properties

No computed properties available.

Protocol Information