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GpCpp
Catalog Number: orb1733950
| Catalog Number | orb1733950 |
|---|---|
| Category | Small Molecules |
| Description | (GMPCPP) |
| Form/Appearance | solution in water; Color: colorless to slightly yellow; pH: 7.5 ± 0.5 |
| Concentration | 10 mM-11 mM |
| Purity | ≥ 95% (HPLC) |
| MW | Theoretical MW: 521.21 g/mol (free acid); Detected MW: 521.01 g/mol (free acid) |
| Application notes | Atomic force microscopy; Cryomicroscopy; Assembly of microtubule; Dynamic of microtubule bundles. Spectroscopic Propertie: λmax 252 nm, ε 13.7 L mmol-1 cm-1 (Tris-HCl, pH 7.5). Specific Ligands: Tubulin, GTP cyclohydrolase. |
| CAS Number | 14997-54-7 |
| Formula | C11H18N5O13P3 |
| SMILES | Nc1nc2c(c(=O)[nH]1)ncn2[C@@H]1O[C@H](COP(=O)(O)CP(=O)(O)OP(=O)(O)O)[C@@H](O)[C@H]1O |
| Storage | store at -20 °C. Short term exposure (up to 1 week cumulative) to ambient temperature possible |
| Note | For research use only |
| Expiration Date | 12 months from date of receipt. |
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GpCpp [orb63468]
≥ 95% (HPLC)
14997-54-7
Theoretical MW: 521.21 g/mol (free acid); Detected MW: 521.01 g/mol (free acid)
C11H18N5O13P3
5 x 100 μl
For example, if the dosage of your experiment is 10mg/kg, the weight of each animal is 50g, and the volume of the dosing is 100μL, then the working solution concentration of your experiment is 5mg/mL. If the formula you used is 5% DMSO+ 30% PEG300+ 5% Tween 80 + 60% Saline/PBS/ddH2O, the preparation method is as follows:
Mother liquor preparation method: 5mg of drug dissolved in 100μL DMSO (mother liquor concentration is 50mg/mL). Preparation method of in vivo formulation: For 1mL of working solution preparation, take 50μL of DMSO mother liquor, add 300 μL of PEG300 to mix well and clarify, then add 50μL of Tween-80 to mix well and clarify, and finally add 600μL of Saline/PBS/ddH2O to mix well and clarify.Note:
- For Reference Only. Please choose the appropriate dissolution protocol according to your experimental animal and administration method.
- We suggest that in cell experiments, the final concentration of DMSO is not more than 0.1%, in animal experiments, for healthy mice, the final concentration of DMSO is not more than 10%; For nude or frail mice, the final concentration of DMSO is not more than 2%.
