GPAT-IN-1

SKU: orb1942499

Description

GPAT-IN-1 is a selective inhibitor of glycerol-3-phosphate acyltransferase, an enzyme critical for triglyceride synthesis. This small molecule tool compound is utilized in metabolic disease research, including in vitro studies of lipogenesis and in vivo models investigating obesity and type 2 diabetes pathways.

Research Area

Metabolism Research

Key Properties

• CAS Number: 1204347-51-2
• MW: 423.95
• Purity: 99.79% (May vary between batches)
• Formula: C₂₁H₂₆ClNO₄S
• SMILES: O=C(O)C=1C=C(C=CC1NS(=O)(=O)CCCCCCCC)C2=CC=CC(Cl)=C2
• Target: Transferase,Others,Acyltransferase
• Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (7.78 mM);DMSO:80 mg/mL (188.7 mM)

Bioactivity

• Target IC50:
  GPAT:8.9 μM
• In Vitro:
  GPAT-IN-1 (Compound 13b) inhibits GPAT with an IC50 of 8.9 μM .

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

GPAT

Compound Identifiers

PubChem CID

44608763