Gomisin G

SKU: orb1296124

Description

Gomisin G is a natural lignan with potent in vitro anti-HIV-1 activity, demonstrating an EC50 of 0.006 µg/mL and a high therapeutic index. It serves as a substrate for CYP2C9 and is a compound of interest for virology and drug metabolism research.

Research Area

Infectious Disease & Virology, Metabolism Research, Protein Biochemistry

Key Properties

• CAS Number: 62956-48-3
• MW: 536.57
• Purity: 99.98% (May vary between batches)
• Formula: C₃₀H₃₂O₉
• SMILES: COc1cc2C[C@H](C)[C@](C)(O)[C@@H](OC(=O)c3ccccc3)c3cc4OCOc4c(OC)c3-c2c(OC)c1OC
• Target: Cytochromes P450,HIV Protease
• Solubility: H2O:Insoluble;DMSO:45 mg/mL (83.87 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (3.73 mM)

Bioactivity

• Target IC50:
  HIV protease:0.006 μg/mL(EC50)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

inhibit, Gomisin G, HIV Protease, HIV, HIVProtease, Human immunodeficiency virus, Inhibitor, CYP2C9

Compound Identifiers

PubChem CID

14992067