Golotimod hydrochloride

SKU: orb1709563

Description

Golotimod hydrochloride (229305-39-9 free base)

Research Area

Infectious Disease & Virology, Signal Transduction, Stem Cell & Developmental Biology

Key Properties

• CAS Number: 1029401-59-9
• MW: 369.8
• Purity: 99.86%
• Formula: C₁₆H₂₀ClN₃O₅
• SMILES: C([C@@H](NC(CC[C@H](C(O)=O)N)=O)C(O)=O)C=1C=2C(NC1)=CC=CC2.Cl
• Target: STAT,Antibacterial
• Solubility: H2O:120 mg/mL (324.5 mM)

Bioactivity

• In Vivo:
  Oral administration of Golotimod hydrochloride at a dose of 5μg/kg after fasting overnight significantly reduced infectional recurrent lesions in recurrent genital HSV-2 guinea pigs. Golotimod hydrochloride is able to alter the duration and severity of oral mucositis and depends on time and dose.
• In Vitro:
  Golotimod hydrochloride can stimulate T helper cells to shift to TH1-like immune response. Golotimod hydrochloride can stimulate macrophage function decreased by TB infection and isoniazid treatment, and improve phagocytosis activity of peritoneal macrophages. It can be used as a prospective immunomodulator for the complex treatment of tuberculosis (TB).

Storage & Handling

• Storage: keep away from moisture,store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

229305-39-9, 229305-39-9 free base, Golotimod hydrochloride (229305 39 9 free base), Golotimod hydrochloride (229305399 free base), Golotimod hydrochloride (229305-39-9 free base), Gamma-D-glutamyl-L-tryptophan hydrochloride, SCV 07 hydrochloride, SCV07 hydrochloride, SCV-07 Hydrochloride, STAT3

Compound Identifiers

PubChem CID

172898589