GNF2133 hydrochloride

SKU: orb1687001

Description

GNF2133 hydrochloride is a potent, selective, and orally bioavailable DYRK1A inhibitor (IC50: 6.2 nM) that enhances primary β-cell proliferation and insulin secretion. It is a valuable research tool for studying glucose homeostasis and pancreatic beta-cell regeneration in models of type 1 diabetes, based on in vitro and in vivo experimental data.

Research Area

Cell Biology, Signal Transduction

Key Properties

• CAS Number: 2561414-57-9
• MW: 471.0
• Formula: C₂₄H₃₁ClN₆O₂
• SMILES: Cl.CCN1CCN(CC1)C(=O)Nc1cc(ccn1)-c1cn(C2CCOCC2)c2cnccc12
• Target: Others,DYRK

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

156015235