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GNF-1331

SKU: orb1697068

Description

GNF-1331 is a potent and selective porcupine inhibitor with an IC50 of 12 nM, demonstrating oral bioavailability. It suppresses aberrant Wnt signaling, a target for oncology research, and has shown efficacy in both cellular assays and in vivo tumor models.

Research Area

Signal Transduction, Stem Cell & Developmental Biology

Images & Validation

Key Properties

CAS Number603101-22-0
MW440.54
FormulaC20H20N6O2S2
SMILESC(CC)N1C(=NN=C1SCC(NC=2SC=3C(N2)=CC=C(OC)C3)=O)C=4C=CN=CC4
TargetOthers,Porcupine,Wnt/beta-catenin

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Key Properties

No computed properties available.

Protocol Information