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GNE-2256

GNE-2256

Catalog Number: orb1744221

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Catalog Numberorb1744221
CategorySmall Molecules
DescriptionGNE-2256, also known as molecule 19, is an orally active compound that inhibits Interleukin 1 receptor-associated kinase 4 (IRAK4) with a K i of 1.4 nM and has an IL-6 inhibition concentration (IC50) of 190 nM.
Purity98.00%
MW482.51
Biological ActivityGNE-2256, also known as molecule 19, is an orally active compound that inhibits Interleukin 1 receptor-associated kinase 4 (IRAK4) with a K i of 1.4 nM and has an IL-6 inhibition concentration (IC50) of 190 nM.
CAS Number2102170-43-2
FormulaC24H27FN6O4
SMILESN(C(=O)C1=C2N(N=C1)C=CC=N2)C3=C(C=C4C(=C3)CN(C[C@H](C(C)(C)O)F)C4=O)N5CCOCC5
Storage-20°C
NoteFor research use only