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Catalog Number | orb1744221 |
---|---|
Category | Small Molecules |
Description | GNE-2256, also known as molecule 19, is an orally active compound that inhibits Interleukin 1 receptor-associated kinase 4 (IRAK4) with a K i of 1.4 nM and has an IL-6 inhibition concentration (IC50) of 190 nM. |
Purity | 98.00% |
MW | 482.51 |
Biological Activity | GNE-2256, also known as molecule 19, is an orally active compound that inhibits Interleukin 1 receptor-associated kinase 4 (IRAK4) with a K i of 1.4 nM and has an IL-6 inhibition concentration (IC50) of 190 nM. |
CAS Number | 2102170-43-2 |
Formula | C24H27FN6O4 |
SMILES | N(C(=O)C1=C2N(N=C1)C=CC=N2)C3=C(C=C4C(=C3)CN(C[C@H](C(C)(C)O)F)C4=O)N5CCOCC5 |
Storage | -20°C |
Note | For research use only |