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GNE 220

SKU: orb1709568

Description

GNE-220 is a highly potent and selective small molecule inhibitor of MAP4K4, demonstrating an IC50 of 7 nM. This compound is a valuable research tool for investigating the role of MAP4K4 in cellular signaling, inflammation, and metabolic disorders in both in vitro and in vivo models.

Research Area

Signal Transduction

Images & Validation

Key Properties

CAS Number1199590-75-4
MW438.53
FormulaC25H26N8
SMILESCC1=C2C(C=3C(N2)=NC=C(C3)C4=CC=C(C=C4)N5CCN(C)CC5)=NC(=N1)C6=CN(C)N=C6
TargetMAPK,Others

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Key Properties

No computed properties available.

Protocol Information